CAD and proof of arrest and reversal 2
"How to reverse Coronary Disease :
Reversing and Preventing
Resolving the Coronary Artery Disease Epidemic through Plant-Based Nutrition"
Atherosclerotic disease is presently
threatens 1 of 2 Americans and will become number one global disease by the year 2020. 1
High fat food causes atherosclerosis. Nutritional studies and population surveys, supports that a plant-based
diet and aggressive lipid lowering to arrest, prevent, and reverse heart disease.
Atherosclerosis is absent in cultures that eat plant-based foods. 2
Atherosclerotic process usually starts
in early childhood.
diseases are treated mainly by
Figure 1 – Coronary angiograms of
the distal left anterior descending artery before (left) and after (right) 32 months of a plant-based diet without cholesterol-lowering
medication, showing profound improvement.
interventional procedures (atherectomy,
angioplasty, stenting, bypass and ballooning) at a cost well over 250 billions dollars.1 Treatment is provided for symtomatic
relief for the patients, usually when coronary arterial stenosis is 70% or more, with great deal of mortality
and morbidity, and at a great cost.This is more of
a palliative care rather than aim for a cure.3 Unfortunately, these interventions bring
only temporary benefit. This traetments do not offer solution for future heart attacks.
Future heart attacks take place
from break away ubstable plaques (without time for collateral circulation formation) causing by 30-40% coronary
arterial stenosis, and usually not by the stenosis over 70%.4, 5
proven way to prevent future heart attacks is by adopting programs recommended by Drs. Ornish and Esselstyn. These programs
aim for a total cholesterol below 150 mgm/Dl and fat content of daily diet of less than 10 Gm. These programs are discussed
in a later chapter.
1-4 are from Dr. Eddelstyn's article and adequtely proves his points that coronary artery diseases can
be arrested and reversed.11
similar to Drs. Ornis's 6 and Esselstyn's programs, other programs, (total cholesterol over 150 mgm and daily
diet fat content over 10 Gm) simply do not work or proven yet.
Figure 2 — Coronary angiograms of
the circumflex artery before (left) and showing 20% improvement (right) following approximately 60 months of a plant-based
diet with cholesterol-lowering medication.
Figure 3-- Coronary angiograms of the proximal left anterior descending artery before (left) and showing
10% improvement (right) following approximately 60 months of a plant-based diet with cholesterol-lowering medication.
Figure 4–Coronary angiograms of right
coronary artery before (left) and showing 30% improvement (right) following approximately 60 months of a plant-based diet
and cholesterol-lowering medication.
Those patients who strictly adhered to Dr. Esselstyn
program, had not had a coronary event after 5, 12 and 20 years.7, 8, 9
Repeat angiography showd either improvement or no progession of the atherosclerotic process among these patients.
Those who dropped out from the program, had multiple coronary events. 7, 8, 9
First National Conference on the Elimination and Prevention of Coronary Artery Disease:
faculty haverecommended 10, 11 ( either to arrest or to prevent coronary artery disease).
The faculty recommended that the diet should consist of grains,
legumes, vegetables, fruit, and calories from fat to be less than 10%-15%. Here, fat in take recommendation quite a
bit higher than that is recommended by Drs. Ornish and Esselstyn. This diet may not achieve as good result as achieved by
Drs. Ornish and Esseltyn. 12
Diet of children and adolescents also need to be addressed to prevent
the start of atheroxclerotic process.
Possible other benefits of this diet are reduction of stroke, obesity, hypertension, type II diabetes, and cancers (breast, prostate,
colon, rectum, uterus, and ovary).
No adverse effects should occur if the diet contains adequat vitamins and minerals.10, 11
1) Braunwald E.
Shattuck Lecture: Cardiovascular medicine at the turn of the millennium: triumphs, concerns and opportunities. N Engl J Med
2) Campbell TC,
Parpia B, Chen J. Diet, lifestyle, and the etiology of coronary artery disease: The Cornell China Study. Am J Card 1998;82(10B):18T-21T.
3) The Bypass
Angioplasty Revascularization Investigation (BARI) Investigators. Comparison of coronary bypass surgery with angioplasty in
patients with multivessel disease. N Engl J Med 1996;335:217-225.
4) Ambrose JA,
Fuster V. Can we predict future coronary events in patients with stable coronary artery disease? JAMA 1997;277:343-344.
5) Forrester JS,
Shah PK. Lipid lowering versus revascularization – an idea whose time for testing has come. Circulation 1997;96:1360-1362.
6) Ornish D, Scherwitz
LW, Billings JH, Gould KL, Merritt TA, Sparler S, Armstrong WT, Ports TA, Kirkeeide RL, Hogeboom C, Brand RJ. Intensive lifestyle
changes for reversal of coronary heart disease. JAMA 1998;280:2001-2007.
7) Esselstyn CB
Jr, Ellis SG, Medendorp SV, Crowe TD. A strategy to arrest and reverse coronary artery disease: a 5-year longitudinal study
of a single physician’s practice. J Fam Prac 1995;41:560-568.
8) Esselstyn CB
Jr. Updating a 12-year experience with arrest and reversal therapy for coronary heart disease (An overdue requiem for palliative
cardiology). Am J Card 1999;84:339-341.
9) Esselstyn CB
Jr. Foreword: Changing the treatment paradigm for coronary artery disease. Am J Card 1998;82(10B):2T-4T.
10) National Research Council (US) Committee on Diet & Health. Diet and health: implications for
reducing chronic disease risk/Committee on Diet and Health, Food and Nutrition Board, Commission on Life Sciences; National
Research Council. Washington, DC: National Academy Press, 1989.
B. Esselstyn, Jr.
Caldwell B. Esselstyn, Jr.Preventive Cardiology
2001; 4: 171-177http://www.jmbblog.com/2009/02/coronary-heart-disease-part-4-you-can-reverse-it/
Coronary Heart Disease Part 4 / you can reverse it
How to reverse Coronary Disease :Reversing and Preventing. Resolving the Coronary Artery Disease Epidemic through Plant-Based NutritionPreventive Cardiology
2001; 4: 171-177 http://www.jmbblog.com/2009/02/coronary-heart-disease-part-4-you-can-reverse-it/
12.In Cholesterol Lowering, Moderation Kills
Caldwell B. Esselstyn, Jr, MD
Department of General Surgery, Cleveland Clinic Foundation