CAD and natural antihypertensives
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Milk and cancer
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Heart disease and gene
CAD and natural antihypertensives


Lifestyle modification:
 an effective method of reducing high blood pressure.24 

Weight loss - Usually, only 10-15 lbs. of weight loss (in overweight subjects) will produce a significant blood pressure reduction in hypertensive patients.

Salt intake - Limit to 2-3 grams per day. Limit alcohol consumption to less than two drinks per day and even less for women. (maximum of nine drinks per week)

Exercise - endurance exercise 30-60 minutes per session a minimum of four times per week.

Calcium supplementation - 1,000-1,500 mg per day (calcium carbonate or citrate), taken in divided doses of 500 mg per dose (with food).

Magnesium supplementation - 600 mg per day (all at once or in divided doses, with food).

Flaxseed Oil - 2,000 mg per day (two 1,000-mg capsules with meals).

Coenzyme Q10 - 60 mg twice per day is a popular treatment for hypertension.

Hawthorn - 75 mg twice per day (standardized to five percent flavanoid content) can be used provided the patient is not also taking digitalis or digoxin.

Garlic extract supplementation (optional) - yielding 4,000 mcg of allicin content.

Fruits and vegetables - at least five servings per day.

The preceding recommendations can be used in conjunction with standard antihypertensive drugs, if necessary. At present, there is sufficient evidence from well-designed medical intervention trials to show that lifestyle interventions are successful in reducing or eliminating the need for pharmacologic therapy in a high percentage of hypertensive patients.29-32

For more information on this or other related topics, go to Dr. Meschino's website

Reduce caffeine,




a) Potassium
b) Magnesium
c) Calcium


a) Pomegranate
b) Water melon

a) Hawthorn

a) CoQ10 

Mayo Clinic 5 Steps to Controlling High Blood Pressure



Did you know that your blood pressure goes down if you make your heart stronger? A strong heart exerts less force on arteries. You'll find dozens of tips to realize this goal.



b) Hydrolyzed Whey Protein
c) Argenine and citruline

Capoten (generic- captopril), belongs to antihypertensive drugs ACE inhibitors. These drugs counteract the action of angiotensin-converting enzymes (ACEs). ACEs  cause blood vessels to constrict.


Pomegranate lowers blood pressure in the same way that Capoten does. Aviram and Dornfeld studied the effects of consumption of the juice on 10 hypertensive adults. Eight had been treated with ACE inhibitors, while the remaining two were on calcium channel blocker therapy. The test subjects who drank 1.7 oz. of pomegranate juice daily for two weeks, averaged 36 percent less ACE in their blood and a 5 percent reduction in systolic blood pressure. Antioxidants property of pomegranate may play a role in lowering BP.


Hawthorn extract can dilate blood vessels and lower blood pressure, (Botanist James A. Duke, author of “The Green Pharmacy Herbal Handbook.”)

Duke recommended to lower high BP: To drink upto 2 cups of tea/day made by steeping 1 tsp. of dried herb per cup of boiling water. 

Shane Elison, author of “Over the Counter Natural Revolution,” :

Hawthorn  does not have unpleasant side effects of ACE inhibitors eg.chronic dry cough, fever, rash and weakness.  The flavonoids in hawthorn is good for cardiovascular health, relaxes the coronary arteries.

CoQ10 and Hydrolyzed Whey Protein 

Both have ACE inhibitor like properties.

 Johnny Bowden author of “Most Effective Natural Cures on Earth,” recommends daily doses of 50 to 300 mg of Coenzyme Q10 and 30 g of hydrolyzed whey protein powder.

  • MedlinePlus: Captopril

  • "Atherosclerosis"; Pomegranate juice consumption inhibits serum angiotensin converting enzyme activity and reduces systolic blood pressure; Michael Aviram and Leslie Dornfeld; September 2001
  • “The Green Pharmacy Herbal Handbook”; James A. Duke; 2000
  • “Over the Counter Natural Revolution”; Shane Elison; 2009
  • “Most Effective Natural Cures on Earth”; Johnny Bowden; 2008

Article reviewed by Roman Tsivkin Last updated on: Jun 30, 2010

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Reducing High Blood Pressure with Natural Therapies

By James P. Meschino, DC, MS

Trends in Hypertension

High blood pressure affects approximately 25 percent of the adult population in developed countries such as the U.S. and Canada. In up to 75 percent of these cases, hypertension manifests in a mild form, which is highly sensitive to nutrition, supplementation and lifestyle practices.1,22 Even the most current medical literature stresses that people with documented hypertension should receive intensive nonpharmacologic therapies to improve control of their condition and reduce the risk of developing further cardiovascular disease.23

Hypertension, hypercholesterolemia and cigarette smoking are considered the cardinal risk factors for cardiovascular disease. Studies indicate that lowering a patient's blood pressure from 160/90 to 140/80 mmHg may decrease risk of heart disease by more than 30 percent.

From a medical standpoint, the use of anti-hypertensive drugs dominates the management of these conditions, and little attention is often given to nutrition and lifestyle approaches. However, many patients discontinue their drug regiment due to side effects from these drugs, which can include fatigue; male impotence; elevated cholesterol levels; light-headedness; dizziness; and skin eruptions.4 In Canada, 22 percent of adults have hypertension, but only 16 percent of this population is treated and controlled. This leaves 84 percent of hypertensive patients uncontrolled and sometimes unaware that this silent killer is even present.5,6 

Effective Nutritional Therapies and Lifestyle Interventions

Weight loss: Hypertensive patients who are overweight experience a drop to normal in their readings in approximately two-thirds of cases by simply losing 10-15 pounds.7,8 Overweight patients tend to display insulin resistance, especially in cases where there is a propensity for abdominal weight gain (android obesity). Insulin resistance results in higher secretion rates of insulin to help overcome the resistance to insulin displayed by peripheral body cells.

One of the consequences of hyperinsulinemia is increased retention of sodium by the kidneys, which tends to drive up blood pressure in sodium-sensitive individuals. Thus, moderate weight loss helps to reverse insulin resistance, lowering basal and postprandial insulin blood levels. This, in turn, encourages less sodium retention and a natural lowering of blood pressure. It is estimated that in up to half of adults in the U.S. whose hypertension is being pharmacologically managed, the need for drug therapy could be alleviated with only modest reductions in body weight.9

In conjunction with dietary advice to help reduce excess weight, engaging in regular endurance-based exercise (at least 40-60 minutes of brisk walking four to five times per week) has been shown to help reduce high blood pressure. Exercise further increases insulin sensitivity, accelerates weight loss and induces other changes within the cardiovascular system to lower blood pressure.6,10 Clearly, health practitioners should become more involved in providing patients with safe and effective nutrition and lifestyle practices that reverse weight gain and enhance the patient's overall level of cardiovascular fitness.

Lower alcohol consumption: Studies indicate that excess alcohol consumption is a culprit in hypertension. Restricting alcohol consumption to two or fewer drinks per day, (fewer than 14 weekly for men, and nine for women) has been shown to help lower blood pressure in individuals who consume alcohol.7

Sodium restriction: Approximately 40-50 percent of hypertensive patients are thought to be sensitive to sodium intake, which is at least a partial cause of their problem. Salt sensitivity appears to be more common among blacks, diabetics and the elderly. Reducing sodium intake to 2000 mg per day is a prudent step in the global management of hypertension. This requires restricted use of discretionary salt, and avoiding heavily salted processed foods. (e.g., prepared soups, pickles, salted snack foods, foods containing MSG, etc.)7,11,12,13

Calcium supplementation: A number of well-designed human intervention trials reveal that calcium supplementation (1,000-1,500 mg calcium per day as calcium carbonate or citrate) can lower blood pressure, particularly in sodium-sensitive hypertensive patients. Calcium encourages sodium excretion by the kidneys and, in concert with magnesium, helps to relax the smooth muscle lining of arterioles, lowering diastolic pressure.11,14,35 Calcium and magnesium supplements are best taken with meals for this purpose, and to enhance their absorption.33

Magnesium supplementation: Supplementation with 600 mg per day of magnesium has been shown to lower blood pressure in some, but not all, studies. Presently, a greater body of evidence exists for calcium supplementation than for magnesium. However, there is no risk in including 600 mg of magnesium in the management of hypertension (unless severe kidney disease is present).15

Omega-3 Fat Supplementation: Over 60 double-blind studies have demonstrated that either fish oil or flaxseed oil supplementation can be effective in lowering blood pressure. One tablespoon per day of flaxseed oil can lower systolic and diastolic blood pressure by up to 9 mm Hg.16 I generally recommend 1,000 mg of flaxseed oil (in capsule form) twice a day with meals.

Garlic extract supplementation: Supplementation with a garlic extract product that yields 4,000 mcg of allicin (between a half and a whole clove of garlic) may help to lower blood pressure. Reductions of 20-30 mm Hg systolic and 10-20 mm Hg diastolic pressure have been demonstrated. However, this effect varies greatly among hypertensive subjects.2,17

Coenzyme Q10 supplementation: In recent years, a number of randomized, double-blind trials have demonstrated that Coenzyme Q10 (CoQ10) supplementation can effectively and consistently lower blood pressure in hypertensive subjects. CoQ10 is directly involved in the bioenergetic pathways of ATP production in heart muscle (myocardium). Research reveals that 39 percent of patients with high blood pressure have a deficiency of CoQ10. Supplementation with CoQ10 appears to correct this deficiency, correcting the underlying metabolic abnormality that leads to high blood pressure development.

Most experts in this field believe that CoQ10 is able to lower blood pressure through its favourable influence on heart bioenergetic mechanisms and possibly relaxing vascular smooth muscle. Because CoQ10 corrects an underlying metabolic defect that leads to high blood pressure, lowering of blood pressure usually requires four to 12 weeks of CoQ10 supplementation.18-21

In a recent randomized, double blind trial among patients receiving antihypertensive medications, the addition of 60 mg of CoQ10, twice daily was shown to markedly reduce both systolic and diastolic blood pressure. CoQ10 supplementation also reduced other risk factors for cardiovascular disease, including a lowering of fasting and two-hour plasma insulin, glucose, triglycerides, lipid peroxides and blood levels of malondialdehyde - a marker of free radical damage.

The authors of the study conclude that CoQ10 decreases blood pressure (possibly by decreasing oxidative stress, i.e., free radical generation) and insulin response in hypertension patients receiving conventional antihypertensive drugs. This study and others provide evidence that CoQ10 can be taken safely in conjunction with antihypertensive drugs to produce better blood pressure lowering outcomes. 22-24

The daily dosage of CoQ10 to aid in lowering blood pressure is usually 60 mg twice per day.22A dosage of 100 mg once per day has been tested.16 In mild cases of hypertension, 30-75 mg once per day may be sufficient to normalize blood pressure.23,24

Hawthorn extract supplementation: The hawthorn plant and its berries are a rich source of a unique strand of bioflavonoids, known as procyanidins. Like CoQ10, these procyanidins have been shown to reverse congestive heart failure by enhancing bioenergetic pathways in the heart muscle (myocardium). More recently, we have seen a number of intervention trials that demonstrate that hawthorn extract supplementation can also effectively reduce high blood pressure.

The procyanidins in hawthorn act as cardiac glycoside agents that increase cyclic AMP and produce a vasodilatation effect on arteries. The daily dosage required to lower blood pressure ranges from 100-250 mg, up to three times daily if taken as a sole antihypertensive agent. To ensure sufficient levels of its active constituents (procyanidins), the product must be standardized to five-percent flavanoid content (1-2% vitexin content). Usually two to four weeks is required to see a significant decline in blood pressure in hypertensive patients.27Hawthorn is contra-indicated in patients taking digitalis or digoxin.34


The World Health Organization has promoted lifestyle modification as an effective method of reducing high blood pressure and overall cardiovascular risk.24 A summary of effective natural antihypertensive interventions include:

Weight loss - Usually, only 10-15 lbs. of weight loss (in overweight subjects) will produce a significant blood pressure reduction in hypertensive patients.

Salt intake - Limit to 2-3 grams per day. Limit alcohol consumption to less than two drinks per day and even less for women. (maximum of nine drinks per week)

Exercise - endurance exercise 30-60 minutes per session a minimum of four times per week.

Calcium supplementation - 1,000-1,500 mg per day (calcium carbonate or citrate), taken in divided doses of 500 mg per dose (with food).

Magnesium supplementation - 600 mg per day (all at once or in divided doses, with food).

Flaxseed Oil - 2,000 mg per day (two 1,000-mg capsules with meals).

Coenzyme Q10 - 60 mg twice per day is a popular treatment for hypertension.

Hawthorn - 75 mg twice per day (standardized to five percent flavanoid content) can be used provided the patient is not also taking digitalis or digoxin.

Garlic extract supplementation (optional) - yielding 4,000 mcg of allicin content.

Fruits and vegetables - at least five servings per day.

The preceding recommendations can be used in conjunction with standard antihypertensive drugs, if necessary. At present, there is sufficient evidence from well-designed medical intervention trials to show that lifestyle interventions are successful in reducing or eliminating the need for pharmacologic therapy in a high percentage of hypertensive patients.29-32

For more information on this or other related topics, go to Dr. Meschino's website


  1. Halpern S. (ed.) Quick reference to clinical nutrition. Nutrition and Cardiovascular Disease; J.B. Lippincott Company, Philadelphia, 1987:139-153.
  2. Canadian Guidelines for Cardiac Rehabilitation and Cardiovascular Disease Prevention(Canadian Assoc. of Cardiac Rehab.) 1st edition, 1999;94-104.
  3. Fowler FE. Myocardial infarction in the 1990s. Postgraduate Medicine May 1995;5:135-146.
  4. Griffith HW. Complete Guide to Prescription and Non-Prescription Drugs (1999 edition) The Body Press 1998:168-169,194-195,54-55.
  5. Murray CJLM, et al. Evidence-based health policy - lessons from the global burden of disease study. Science 1996;274:740-743.
  6. Joffres MR, et al. Awareness, treatment, and control of hypertension in Canada. Am J Hypertens 1997;10(Pt-1):1097-1102.
  7. 2000 Canadian hypertension recommendations (summary of recommendations affecting family physicians) - the Canadian Hypertension Recommendations Working Group.Canadian Family Physician. April 2001;47:793-794.
  8. Goodhart R, Shils M, Lea, Febiger. Modern Nutrition in Health and Disease (sixth edition): 733.
  9. McCarron D, et al. Body weight and blood pressure regulation. Am J Clin Nutr 1996; 63(suppl):423-425.
  10. Pate RR, et al. Physical Activity and public health. JAMA Feb. 1, 1995;272,5:402-407.
  11. McCarron D. Role of adequate dietary calcium intake in the prevention and management of salt-sensitive hypertension. Am J Clin Nutr 1997;62: 2(suppl):712-716.
  12. Cappuccio F, et al. Double-blind randomized trial of modest salt restriction in older people.Lancet 1997;350;9081:850-854.
  13. Graudal N, et al. Effects of sodium restriction on blood pressure, rennin, aldosterone, catecholamines, cholesterols, and triglycerides. JAMA 1998;279:1383-1391.
  14. Meese RB, et al. The inconsistent effects of calcium supplements upon blood pressure in primary hypertension. Am J Med Sci 1987;29:4219-4224.
  15. Motoyama T, et al. Oral magnesium supplementation in patients with essential hypertension. Hypertension1989;13:227-232.
  16. Murray M, Pizzorno J. Encyclopedia of Natural Medicine (2nd edition) Prima Publishing 1997;425-535.
  17. Foushee DB, et al. Garlic as a natural agent for the treatment of hypertension. A preliminary report. Cytobios 1982;34:145-162.
  18. Digiesi V, et al. Mechanism of action of Coenzyme Q10 in essential hypertension. Curr Ther Res 1992;Res 51:668-672.
  19. Langsjoen P, et al. Treatment of essential hypertension with Coenzyme Q10. Mol Aspects Med 1994 Med 15 (suppl):265-272.
  20. Digiesi V, et al. Coenzyme Q10 in essential hypertension. Mol Aspects Med 1994; Med 15 (suppl):257-263.
  21. McCarty MF. Coenzyme Q versus hypertension: does CoQ decrease endothelial superoxide generation? Med Hypotheses 1999;53,4:300-304.
  22. Singh RB, et al. Effect of hydrosoluble Coenzyme Q10 on blood pressure and insulin resistance in hypertensive patients with coronary artery disease. J Hum Hypertens1999;13,3:203-208.
  23. Yamagami T, et al. Bioenergetics in clinical medicine: studies on coenzyme Q10 and essential hypertension. Research Comm. in Chem. Path and Pharmacol 1975;11,2: 273-288.
  24. Yamagami T, et al. Bioenergetics in clinical medicine, VIII. Administration of Coenzyme Q10 to patients with essential hypertension. Research Comm in Chem Path and Pharmacol1976;14,4:721-727.
  25. Murray M. Encyclopedia of Nutritional Supplements. PRIMA publishing 1996:300-301.
  26. Werbach MR. Nutritional Influences on Illness. Third Line Press, Inc. 1987:227-240.
  27. Murray M, Pizzorno J. Encyclopedia of Natural Medicine (2nd edit) Prima Publishing 1997:524-535.
  28. Petrella RJ. Lifestyle approaches to managing high blood pressure. Can Family Phys1999;45:1750-1755.
  29. Elmer JP, et al. Lifestyle intervention: results of the Treatment of Mild Hypertension study. (TOHMS). Prev Med 1995;24:378-388.
  30. Stamler R, et al. Nutritional therapy for high blood pressure. Final report of a four-year randomized controlled trial - the hypertension control program. JAMA 1987;257:1484-1491.
  31. Iso H, et al. Community-based education classes for hypertension control: a 1.5-year randomized controlled trial. Hypertension 1996;27:968-974.
  32. Appel LJ, et al. A clinical trial of the effects of dietary patterns on blood pressure (DASH-study) N Engl J Med 1997;336:1117-1124.
  33. Levenson D, et al. A review of calcium preparations. Nutr Reviews 1994;52,7:221-232.
  34. Shariff S, et al. Herbal fervor and vitamin vigor: Herbs and vitamins for cardiac disease.Perspective in Cardiology 2000;16,1:21-29.
  35. McCarron D, et al. Blood pressure response to oral calcium in persons with mild to moderate hypertension. A randomized, double-blind, placebo-controlled, crossover trial.Ann Intern Med 1985;03,6:825-831.
  36. ========================


One very important mineral for regulating blood pressure is magnesium. Unfortunately, magnesium also represents one of the most common nutritional deficiencies in those who follow the Standard American Diet. There appears to be an inverse relationship between blood pressure and blood levels of magnesium. Furthermore, the Honolulu Heart Study showed that magnesium intake had the strongest association with blood pressure out of 60 other variables that were evaluated.

Various other studies indicate that magnesium supplementation reduces both systolic and diastolic blood pressure. Around 600 mg per day seems to be the typical dosage for those supplementing with magnesium. When taking magnesium, you should be aware that large single doses may cause diarrhea. Therefore, it might be best to take 200-300 mg, two to three times per day.

Ascorbic acid, or vitamin C, has numerous beneficial properties, so it is no surprise to see it on a list for hypertension. The amazing thing about ascorbic acid is that it has some role to play in nearly every biochemical reaction within our bodies. Understanding this gives an appreciation for the profound health effects that it is capable of producing. In the case of hypertension, vitamin C is thought to exert its effects by enhancing nitric oxide (NO) production. NO is required for dilation of blood vessels, and this dilation reduces blood pressure. Like magnesium, vitamin C blood levels have an inverse relationship with blood pressure. The goal, of course, is to get those vitamin C levels up in order to bring blood pressure down. A complete discussion on dosing vitamin C would require an entire article in and of itself. For more information please see the references below.

An additional nutritional supplement that has shown effectiveness against hypertension is coenzyme Q10 (CoQ10). The general dosage for CoQ10 is around 100-200 mg per day. Note that CoQ10 is a fat-soluble substance and should be taken with food containing some fats or oils for maximum absorption.

The subject of oils brings us to the next superstar for bringing down high blood pressure. Fish oils, specifically the omega-3's (EPA and DHA), have proven antihypertensive benefits. In fact, the benefits of these substances are so well-established that Big Pharma decided to make a version of their own. It is marketed toward reducing high triglyceride levels. You can check it out for yourself here: ( .

It appears that the omega-3 fats are capable of improving the elasticity of arteries, thus allowing the arteries to "absorb more shock" from the force of blood pumping through them. This results in decreased vascular resistance, which leads to reduced blood pressure. The amount of EPA or DHA taken daily can range from 3g to 15g.

Finally, garlic deserves a mention among nutritional agents that can be used to address high blood pressure. The overall effect of garlic on blood pressure may not be as pronounced as that of the previously discussed nutrients. However, it has demonstrated effectiveness in lowering systolic and diastolic blood pressure. The studies utilized doses ranging from 600-900 mg of garlic extract daily.

In conclusion, those individuals who are currently taking antihypertensive drugs should be aware that these nutrients have the potential to significantly lower blood pressure without the need of pharmaceuticals. For this reason, it may become necessary to reduce the drug dosage, or to discontinue the medication entirely. It is advisable to consult your physician regarding supplementation and any changes in therapy.

To your health!


Pelton, Ross. "Nutrients to Reduce Hypertension." Pharmacy Times, January 2005., "High Blood Pressure"

Linus Pauling Institute, "Vitamin C"

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Natural Hypertension treatment and remedy - Diet and food selection
Eat more fruits and vegetables -- preferably fresh and organic. Fruits and vegetables have numerous compounds that can dilate blood vessels, including flavonoids. Fortunately for many chocoholics, cocoa, or dark chocolate, has important flavonoids. Eat more garlic since garlic may reduce hypertension. Berries, such as blueberries, are also known to reduce blood pressure.
Reduce salt intake. Individuals with high blood pressure uncontrolled by multiple prescription medications may be consuming too much salt. Some with so-called resistant hypertension have sharp reductions in their blood pressure when they dramatically curtail their salt intake. If Americans were to cut their salt intake to recommended levels, they'd have far fewer cases of high blood pressure, and save billions of dollars in health care costs. American Journal of Health Promotion, September / October 2009.
Try to shed some pounds -- 
Greater amounts of fat in the abdomen point to an increased risk of developing hypertension. For suggestions, see Weight loss
Reduce fat intake, such as meats, lard, bacon, hydrogenated oils -- fats found in fish are good.
Reduce caffeine-intake -- skip that second cup of coffee, substitute caffeine-free herbal drinks, limit herbal teas with caffeine to one or two cups. Caffeine found in coffee can raise blood pressure in some individuals, even if they are regular drinkers.
Reduce sugar intake - Eating too many sweets or drinking too much soda raises blood sugar. People who consume a diet high in fructose, a type of sugar and a key ingredient in high-fructose corn syrup, are more likely to have hypertension. Drink more water and avoid sodas except small amounts of diet soda which should not raise blood pressure. 
Learn how to sleep better and deeper. Those who sleep deep have a lower risk for hypertension.
Reduce alcohol intake. High amounts of alcohol can certainly aggravate hypertension. Despite its heart benefits, drinking red wine raises blood pressure to the same degree as drinking beer.
Reduce or stop smoking
Try to have less stress in your daily life
Exercise, walk at least one mile per day
Drink unsweetened soy milk and reduce intake of regular milk. 
The use of soy protein dietary supplements may help reduce systolic and diastolic blood pressure in patients with early hypertension, July, 2005 issue of the Annals of Internal Medicine.
Eating dark chocolate may help lower blood pressure, boost normal responses to insulin to keep blood sugar levels down, and improve blood vessel function in patients with high blood pressure.
Yoga helps those with hypertension
Hypertension treatment with diet and supplements, vitamins, herbs, alternative therapies - natural therapy and home remedy by Ray Sahelian, M.D.

Hypertension Research studies
Short-term administration of dark chocolate is followed by a significant increase in insulin sensitivity and a decrease in blood pressure in healthy persons.
Am J Clin Nutr. 2005. 
Numerous studies indicate that flavanols may exert significant vascular protection because of their antioxidant properties and increased nitric oxide bioavailability.. The objective was to compare the effects of either dark or white chocolate bars on blood pressure and glucose and insulin responses to an oral-glucose-tolerance test in healthy subjects. After a 7-d cocoa-free run-in phase, 15 healthy subjects were randomly assigned to receive for 15 d either 100 g dark chocolate bars, which contained approximately 500 mg polyphenols, or 90 g white chocolate bars, which presumably contained no polyphenols. Dark, but not white, chocolate decreases blood pressure and improves insulin sensitivity in healthy persons.

Higher intake of folic acid is associated with a decreased risk of developing hypertension, particularly among younger women.

Randomized, double-blind, placebo-controlled trial of coenzyme Q10 in isolated systolic hypertension.
South Med J. 2001. 
Increasing numbers of the adult population are using alternative or complementary health resources in the treatment of chronic medical conditions. Systemic hypertension affects more than 50 million adults and is one of the most common risk factors for cardiovascular morbidity and mortality. This study evaluates the antihypertensive effectiveness of oral coenzyme Q10 (CoQ), an over-the-counter nutritional supplement, in a cohort of 46 men and 37 women with isolated systolic hypertension. We conducted a 12-week randomized, double-blind, placebo-controlled trial with twice daily administration of 60 mg of oral CoQ and determination of plasma CoQ levels before and after the 12 weeks of treatment. The mean reduction in systolic blood pressure of the CoQ-treated group was 17.8 +/- 7.3 mm Hg (mean +/- SEM). None of the patients exhibited orthostatic blood pressure changes. Our results suggest CoQ may be safely offered to hypertensive patients as an alternative treatment option.

Clinical efficacy of magnesium supplementation in patients with type 2 diabetes.
J Am Coll Nutr. 2004. 
Effects of magnesium (Mg) supplementation on nine mild type 2 diabetic patients with stable glycemic control were investigated. Water from a salt lake with a high natural Mg content (7.1%) (MAG21) was used for supplementation after dilution with distilled water to 100mg/100mL; 300mL/day was given for 30 days. Fasting serum immunoreactive insulin level decreased significantly. There was also a marked decrease of the mean triglyceride level after supplementation. The patients with hypertension showed significant reduction of systolic, diastolic, and mean blood pressure. The salt lake water supplement, MAG21, exerted clinical benefit as a Mg supplement in patients with mild type 2 diabetes mellitus.

Cold weather snaps can trigger heart attacks, particularly in people suffering from hypertension. The increased rate of attacks seen during wintertime lows is probably due to the fact that cold temperatures increase blood pressure and put more strain on the heart.

High blood levels of uric acid is correlated with obesity and hypertension.

The protective effect of habitual tea consumption on hypertension.
Arch Intern Med. 2004.
Tea has long been believed to possess hypertension relieveing effects in popular Chinese medicine. However, conflicting results have been shown among human trials and animal studies on the relation between tea consumption and blood pressure. Epidemiological evidence about the long-term effect of tea on hypertensive risk is also inconsistent. We examined the effect of tea drinking, measured in detail for the past decades, on the risk of newly diagnosed hypertension in 1507 subjects (711 men and 796 women), 20 years or older, who did not have a hypertensive history during 1996 in Taiwan. Six hundred subjects (39.8%) were habitual tea drinkers, defined by tea consumption of 120 mL/d or more for at least 1 year. Compared with nonhabitual tea drinkers, the risk of developing hypertension decreased by 46% for those who drank 120 to 599 mL/d and was further reduced by 65% for those who drank 600 mL/d or more after carefully adjusting for age, sex, socioeconomic status, family history of hypertension, body mass index, waist-hip ratio, lifestyle factors (total physical activity, high sodium intake, cigarette smoking, alcohol consumption, and coffee drinking), and dietary factors (vegetable, fruit, unrefined grain, fish, milk, visible-fat food, and deep fried food intake). However, tea consumption for more than 1 year was not associated with a further reduction of hypertension risk. Habitual moderate strength green or oolong tea consumption, 120 mL/d or more for 1 year, significantly reduces the risk of developing hypertension in the Chinese population.

Pycnogenol, French maritime pine bark extract, improves endothelial function of hypertensive patients.
Life Sci. 2004 Jan.
A placebo-controlled, double-blind, parallel group study was performed with 58 patients to investigate effects of French maritime pine bark extract, Pycnogenol, on patients with hypertension. Supplementation of the patients with 100 mg Pycnogenol over a period of 12 weeks helped to reduce the dose of the calcium antagonist nifedipine in a statistically significant manner. Study results support a supplementation with Pycnogenol for mildly hypertensive patients.

Daily nighttime melatonin reduces blood pressure in male patients with essential hypertension.
Netherlands Institute for Brain Research, Amsterdam, The Netherlands.
Hypertension. 2004.
Patients with essential hypertension have disturbed autonomic cardiovascular regulation and circadian pacemaker function. Recently, the biological clock was shown to be involved in autonomic cardiovascular regulation. Our objective was to determine whether enhancement of the functioning of the biological clock by repeated nighttime melatonin intake might reduce ambulatory blood pressure in patients with essential hypertension. We conducted a randomized, double-blind, placebo-controlled, crossover trial in 16 men with untreated essential hypertension to investigate the influence of acute (single) and repeated (daily for 3 weeks) oral melatonin (2.5 mg) intake 1 hour before sleep on 24-hour ambulatory blood pressure and actigraphic estimates of sleep quality. Repeated melatonin intake reduced systolic and diastolic blood pressure during sleep by 6 and 4 mm Hg, respectively. The treatment did not affect heart rate. The day-night amplitudes of the rhythms in systolic and diastolic blood pressures were increased by 15% and 25%, respectively. A single dose of melatonin had no effect on blood pressure. Repeated (but not acute) melatonin also improved sleep. Improvements in blood pressure and sleep were statistically unrelated. In patients with essential hypertension, repeated bedtime melatonin intake significantly reduced nocturnal blood pressure. Future studies in larger patient group should be performed to define the characteristics of the patients who would benefit most from melatonin intake. The present study suggests that support of circadian pacemaker function may provide a new strategy in the treatment of essential hypertension.

In a major study of blood pressure drugs, patients treated with water pills, or "diuretics," were at increased risk of developing diabetes, according to research presented at the annual scientific meeting of the American Society of Hypertension. But Dr. Joshua Barzilay, from Emory University in Atlanta, said that the increase in diabetes did not translate into an increased risk of heart attack or stroke. In the 42,000-patient study, known as ALLHAT, researchers compared four types of blood pressure drugs: a diuretic, an alpha-blocker, a calcium channel blocker, and an ACE inhibitor. After two years of treatment, 9.3 percent of patients who received a diuretic called Hygroton (chlorthalidone) developed diabetes. In contrast, with the other drugs no more than 7 percent of patients developed diabetes. By 4 years, the difference was still apparent. Barzilay suggested that further studies might be able to determine if costs are increased because those patients who develop diabetes need further treatments.

Soy Milk and  Hypertension
Soy milk drinkers have reason to raise their cup and cheer. A recent three month double blind study completed at the School of Medicine in Zaragoza, Spain tested the effect of 500 ml (about a pint) of soy milk compared with the same amount of cow’s milk in 40 men and women with mild-to-moderate hypertension. Before initiation of the study, urinary isoflavonoids (soy contains compounds called isoflavonoids, the best known being genistein) were undetectable in most cases, meaning that their diet contained little or no soy products. After three months of soy milk consumption, systolic blood pressure decreased by 18 mmHg compared with 2 mmHg in the cow’s milk group. Diastolic blood pressure decreased by 15 mmHg versus 4 mmHg in the cow’s milk group. The researchers conclude that chronic soy milk consumption lowers blood pressure in those with hypertension. This blood pressure-lowering action was correlated with the urinary excretion of the isoflavonoid genistein, meaning that the more genistein excreted in the urine (reflecting the higher amount in the body), the lower the blood pressure. 
Dr. Sahelian says: Those who drink large amounts of milk should consider reducing their milk consumption and partially or mostly substituting soy milk instead. Try soy milk brands that have a minimal amount of added sugar. Use stevia drops for additional sweetness.

Therapeutic potential of yoga practices in modifying cardiovascular risk profile in middle aged men and women.
J Assoc Physicians India. 2002.
To study effect of yoga on the physiological, psychological well being, psychomotor parameter and modifying cardiovascular risk factors in mild to moderate hypertensive patients. Twenty patients (16 males, 4 females) in the age group of 35 to 55 years with mild to moderate essential hypertension underwent yogic practices daily for one hour for three months.  Yoga can play an important role in risk modification for cardiovascular diseases in mild to moderate hypertension.

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